ELISA Substrates and Reagents
![ABclonal Technology [KO Validated] ERK2 Rabbit pAb](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000136563.jpg-250.jpg)
ABclonal Technology [KO Validated] ERK2 Rabbit pAb
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
Echelon Biosciences Research Labs ADAM substrate - 1 mg,
ADAM substrate - 1mg , Glu(EDANS)-Lys-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys(Dabcyl)-NH2 Category/Application: Enzyme Substrates This item is non returnable
Sino Biological Recombinant Human BAFF/BLyS/TNFSF13B Protein (ECD), Endotoxin-Free
A DNA sequence encoding the soluble form of human BAFF (Q9Y275-1) (Ala 134-Leu 285) was expressed and purified.
Enzo Life Sciences ADAM substrate (fluorogenic) (1mg)
Fluorogenic substrate for ADAM8 (kcat/Km = 1.0 x 105 M-1s-1), ADAM10 (6.2 x 103), ADAM12 (2.8 x 105), TACE (TNF-α converting enzyme, ADAM17) (4.3 x 105), and likely other ADAMs, especially those that cleave TNF-α type sequences. Also efficiently cleaved by MMP-1, MMP-2, MMP-3, MMP-8, MMP-9, MMP-13, and MMP-14. FAM fluorescence is quenched by the Dabcyl group until cleavage separates them. Ex.: 485nm, Em.: 530nm. This substrate is useful for inhibitor screening and kinetic analysis. Purity: ≥95% (HPLC). Solubility: Soluble in DMSO (≥10mM) or TRIS, pH 8.0 assay buffer (≥10μM). Long Term Storage: -20°C.